Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgf8  fibroblast growth factor 8   (Synonyms: Aigf, Fgf-8)
Results	Reference
1	J:100575 Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP, Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92
1	J:213642 Cooper KL, Sears KE, Uygur A, Maier J, Baczkowski KS, Brosnahan M, Antczak D, Skidmore JA, Tabin CJ, Patterning and post-patterning modes of evolutionary digit loss in mammals. Nature. 2014 Jul 3;511(7507):41-5
1	J:263988 Gao B, Ajima R, Yang W, Li C, Song H, Anderson MJ, Liu RR, Lewandoski MB, Yamaguchi TP, Yang Y, Coordinated directional outgrowth and pattern formation by integration of Wnt5a and Fgf signaling in planar cell polarity. Development. 2018 Apr 13;145(8):dev163824
1	J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57
1	J:48055 Hecksher-Sorensen J, Hill RE, Lettice L, Double labeling for whole-mount in situ hybridization in mouse. Biotechniques. 1998 Jun;24(6):914-6, 918
1	J:58673 Heymer J, Ruther U, Syndactyly of Ft/+ mice correlates with an imbalance in bmp4 and fgf8 expression. Mech Dev. 1999 Nov;88(2):173-81
1	J:232412 Jeon S, Seong RH, Anteroposterior Limb Skeletal Patterning Requires the Bifunctional Action of SWI/SNF Chromatin Remodeling Complex in Hedgehog Pathway. PLoS Genet. 2016 Mar;12(3):e1005915
1*	J:58081 Lettice L, Hecksher-Sorensen J, Hill RE, The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs. Development. 1999 Nov;126(21):4729-36
1	J:184012 Lopez-Rios J, Speziale D, Robay D, Scotti M, Osterwalder M, Nusspaumer G, Galli A, Hollander GA, Kmita M, Zeller R, GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. Dev Cell. 2012 Apr 17;22(4):837-48
1	J:144308 Ovchinnikov DA, Selever J, Wang Y, Chen YT, Mishina Y, Martin JF, Behringer RR, BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Dev Biol. 2006 Jul 1;295(1):103-15
1	J:52453 Sharpe J, Lettice L, Hecksher-Sorensen J, Fox M, Hill R, Krumlauf R, Identification of sonic hedgehog as a candidate gene responsible for the polydactylous mouse mutant Sasquatch. Curr Biol. 1999 Jan 28;9(2):97-100
1	J:87225 Suzuki K, Bachiller D, Chen YP, Kamikawa M, Ogi H, Haraguchi R, Ogino Y, Minami Y, Mishina Y, Ahn K, Crenshaw EB 3rd, Yamada G, Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia: development by concerted actions of BMP signaling. (Erratum). Development. 2003 Dec;130(25):6209-20
1*	J:306252 Tissieres V, Geier F, Kessler B, Wolf E, Zeller R, Lopez-Rios J, Gene Regulatory and Expression Differences between Mouse and Pig Limb Buds Provide Insights into the Evolutionary Emergence of Artiodactyl Traits. Cell Rep. 2020 Apr 7;31(1):107490
1	J:138578 Verheyden JM, Sun X, An Fgf/Gremlin inhibitory feedback loop triggers termination of limb bud outgrowth. Nature. 2008 Jul 31;454(7204):638-41
1*	J:327901 Ye Q, Bhojwani A, Hu JK, Understanding the development of oral epithelial organs through single cell transcriptomic analysis. Development. 2022 Aug 15;149(16):dev200539
1*	J:150728 Zhao J, Ding J, Li Y, Ren K, Sha J, Zhu M, Gao X, HnRNP U mediates the long-range regulation of Shh expression during limb development. Hum Mol Genet. 2009 Aug 15;18(16):3090-7